Inhibition of FGFR Signaling by Targeting FGF/FGFR Extracellular Interactions: Towards the Comprehension of the Molecular Mechanism through NMR Approaches

NMR-based approaches play a pivotal role in providing insight into molecular recognition mechanisms, affording the required atomic-level description and enabling the identification of promising inhibitors of protein–protein interactions. The aberrant activation of the fibroblast growth factor 2 (FGF...

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Detalles Bibliográficos
Autores principales: Pagano, Katiuscia, Longhi, Elisa, Molinari, Henriette, Taraboletti, Giulia, Ragona, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503799/
https://www.ncbi.nlm.nih.gov/pubmed/36142770
http://dx.doi.org/10.3390/ijms231810860