Cargando…

Metabolomics as a Crucial Tool to Develop New Therapeutic Strategies for Neurodegenerative Diseases

Neurodegenerative diseases (NDs), such as Alzheimer’s (AD), Parkinson’s (PD), and amyotrophic lateral sclerosis (ALS), share common pathological mechanisms, including metabolism alterations. However, their specific neuronal cell types affected and molecular biomarkers suggest that there are both com...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lanznaster, Débora, Dingeo, Giulia, Samey, Rayhanatou Altine, Emond, Patrick, Blasco, Hélène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503806/ https://www.ncbi.nlm.nih.gov/pubmed/36144268 http://dx.doi.org/10.3390/metabo12090864

Ejemplares similares

Metabolomics Biomarkers: A Strategy Toward Therapeutics Improvement in ALS
por: Lanznaster, Débora, et al.
Publicado: (2018)

Metabolomics: A Tool to Understand the Impact of Genetic Mutations in Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2020)

Conditioned Medium from Cells Overexpressing TDP-43 Alters the Metabolome of Recipient Cells
por: Hergesheimer, Rudolf, et al.
Publicado: (2020)

Immediate-Early Modifications to the Metabolomic Profile of the Perilymph Following an Acoustic Trauma in a Sheep Model
por: Boullaud, Luc, et al.
Publicado: (2022)

TDP-43-Mediated Toxicity in HEK293T Cells: A Fast and Reproducible Protocol To Be Employed in the Search of New Therapeutic Options against Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2019)

Is There a Role for Vitamin D in Amyotrophic Lateral Sclerosis? A Systematic Review and Meta-Analysis
por: Lanznaster, Débora, et al.
Publicado: (2020)

Relationship between Metabolomics Profile of Perilymph in Cochlear-Implanted Patients and Duration of Hearing Loss
por: Trinh, Thuy-Trân, et al.
Publicado: (2019)

Cannabis sativa and Cannabidiol: A Therapeutic Strategy for the Treatment of Neurodegenerative Diseases?
por: Viana, Milena de Barros, et al.
Publicado: (2022)

Antioxidant Therapeutic Strategies in Neurodegenerative Diseases
por: Morén, Constanza, et al.
Publicado: (2022)

Metabolic Profile and Pathological Alterations in the Muscle of Patients with Early-Stage Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2022)

Specific Metabolome Profile of Exhaled Breath Condensate in Patients with Shock and Respiratory Failure: A Pilot Study
por: Fermier, Brice, et al.
Publicado: (2016)

Animal Toxins as Therapeutic Tools to Treat Neurodegenerative Diseases
por: de Souza, Jessica M., et al.
Publicado: (2018)

The debated toxic role of aggregated TDP-43 in amyotrophic lateral sclerosis: a resolution in sight?
por: Hergesheimer, Rudolf C, et al.
Publicado: (2019)

An Overview of Crucial Dietary Substances and Their Modes of Action for Prevention of Neurodegenerative Diseases
por: Pogačnik, Lea, et al.
Publicado: (2020)

Guanosine: a Neuromodulator with Therapeutic Potential in Brain Disorders
por: Lanznaster, Débora, et al.
Publicado: (2016)

Aβ1-42 and Tau as Potential Biomarkers for Diagnosis and Prognosis of Amyotrophic Lateral Sclerosis
por: Lanznaster, Débora, et al.
Publicado: (2020)

The Roles of NEDD4 Subfamily of HECT E3 Ubiquitin Ligases in Neurodevelopment and Neurodegeneration
por: Haouari, Shanez, et al.
Publicado: (2022)

Taking Advantages of Blood–Brain or Spinal Cord Barrier Alterations or Restoring Them to Optimize Therapy in ALS?
por: Alarcan, Hugo, et al.
Publicado: (2022)

Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases
por: Haney, Matthew J., et al.
Publicado: (2013)

Tauroursodeoxycholic acid: a potential therapeutic tool in neurodegenerative diseases
por: Khalaf, Kareem, et al.
Publicado: (2022)

Glymphatic System and Mitochondrial Dysfunction as Two Crucial Players in Pathophysiology of Neurodegenerative Disorders
por: Kopeć, Kamila, et al.
Publicado: (2023)

Exosomes as crucial emerging tools for intercellular communication with therapeutic potential in ovarian cancer
por: Malgundkar, Shika Hanif, et al.
Publicado: (2023)

Therapeutic Prospect of New Probiotics in Neurodegenerative Diseases
por: Bi, Mingxia, et al.
Publicado: (2023)

SHR/NCrl rats as a model of ADHD can be discriminated from controls based on their brain, blood, or urine metabolomes
por: Dupuy, Camille, et al.
Publicado: (2021)

A Pivotal Role of Nrf2 in Neurodegenerative Disorders: A New Way for Therapeutic Strategies
por: Suzen, Sibel, et al.
Publicado: (2022)

Photo-Oxygenation as a New Therapeutic Strategy for Neurodegenerative Proteinopathies by Enhancing the Clearance of Amyloid Proteins
por: Tomizawa, Ikumi, et al.
Publicado: (2022)

(1)H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis
por: Blasco, Hélène, et al.
Publicado: (2010)

Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
por: Ciechanover, Aaron, et al.
Publicado: (2015)

Therapeutic potential of systemic brain rejuvenation strategies for neurodegenerative disease
por: Horowitz, Alana M., et al.
Publicado: (2017)

Current and future therapeutic strategies for the treatment of retinal neurodegenerative diseases
por: Maneu, Victoria, et al.
Publicado: (2021)

Regulation of neuronal bioenergetics as a therapeutic strategy in neurodegenerative diseases
por: Onyango, Isaac G., et al.
Publicado: (2021)

Therapeutic antibodies – natural and pathological barriers and strategies to overcome them
por: Al Ojaimi, Yara, et al.
Publicado: (2022)

Correction: (1)H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis
por: Blasco, Hélène, et al.
Publicado: (2010)

Advances in Proteomic and Metabolomic Profiling of Neurodegenerative Diseases
por: Schumacher-Schuh, Artur, et al.
Publicado: (2022)

Salivary Metabolomics in the Diagnosis and Monitoring of Neurodegenerative Dementia
por: Hyvärinen, Eelis, et al.
Publicado: (2023)

Targeting the guanine-based purinergic system in Alzheimer's disease
por: Lanznaster, Débora, et al.
Publicado: (2017)

Nanotherapeutic and Stem Cell Therapeutic Strategies in Neurodegenerative Diseases: A Promising Therapeutic Approach
por: Wei, Min, et al.
Publicado: (2023)

Optimization of Sample Preparation for Metabolomics Exploration of Urine, Feces, Blood and Saliva in Humans Using Combined NMR and UHPLC-HRMS Platforms
por: Martias, Cécile, et al.
Publicado: (2021)

Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies
por: Facecchia, Katie, et al.
Publicado: (2011)

Mitochondrial Quality Control Strategies: Potential Therapeutic Targets for Neurodegenerative Diseases?
por: Hu, Di, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mouj25c56vnkl027soakhdn3d5