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Oral Nanomedicines for siRNA Delivery to Treat Inflammatory Bowel Disease
RNA interference (RNAi) therapies have significant potential for the treatment of inflammatory bowel diseases (IBD). Although administering small interfering RNA (siRNA) via an oral route is desirable, various hurdles including physicochemical, mucus, and cellular uptake barriers of the gastrointest...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503894/ https://www.ncbi.nlm.nih.gov/pubmed/36145716 http://dx.doi.org/10.3390/pharmaceutics14091969 |