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Potential Coronaviral Inhibitors of the Nucleocapsid Protein Identified In Silico and In Vitro from a Large Natural Product Library
The nucleocapsid protein (NP) is one of the main proteins out of four structural proteins of coronaviruses including the severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, discovered in 2019. NP packages the viral RNA during virus assembly and is, therefore, indispensable for virus reprodu...
Autores principales: | Pohler, Alexandra, Abdelfatah, Sara, Riedl, Max, Meesters, Christian, Hildebrandt, Andreas, Efferth, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503946/ https://www.ncbi.nlm.nih.gov/pubmed/36145267 http://dx.doi.org/10.3390/ph15091046 |
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