Secondary Mitochondrial Dysfunction as a Cause of Neurodegenerative Dysfunction in Lysosomal Storage Diseases and an Overview of Potential Therapies

Mitochondrial dysfunction has been recognised a major contributory factor to the pathophysiology of a number of lysosomal storage disorders (LSDs). The cause of mitochondrial dysfunction in LSDs is as yet uncertain, but appears to be triggered by a number of different factors, although oxidative str...

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Detalles Bibliográficos
Autores principales: Stepien, Karolina M., Cufflin, Neve, Donald, Aimee, Jones, Simon, Church, Heather, Hargreaves, Iain P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9503973/
https://www.ncbi.nlm.nih.gov/pubmed/36142486
http://dx.doi.org/10.3390/ijms231810573

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