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Restoration of Cathepsin D Level via L-Serine Attenuates PPA-Induced Lysosomal Dysfunction in Neuronal Cells
L-serine is a non-essential amino acid endogenously produced by astrocytes and is abundant in human diets. Beneficial roles of the metabolic products from L-serine in various conditions in the brain including neuronal development have been reported. Through several preclinical studies, L-serine trea...
Autores principales: | Jeon, Hyunbum, Kim, Yeo Jin, Hwang, Su-Kyeong, Seo, Jinsoo, Mun, Ji Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504002/ https://www.ncbi.nlm.nih.gov/pubmed/36142514 http://dx.doi.org/10.3390/ijms231810613 |
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