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The CFTR Amplifier Nesolicaftor Rescues TGF-β1 Inhibition of Modulator-Corrected F508del CFTR Function

Highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators have led to dramatic improvements in lung function in many people with cystic fibrosis (PwCF). However, the efficacy of CFTR modulators may be hindered by persistent airway inflammation. The cytokine transforming...

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Detalles Bibliográficos
Autores principales:	Bengtson, Charles, Silswal, Neerupma, Baumlin, Nathalie, Yoshida, Makoto, Dennis, John, Yerrathota, Sireesha, Kim, Michael, Salathe, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504033/ https://www.ncbi.nlm.nih.gov/pubmed/36142862 http://dx.doi.org/10.3390/ijms231810956

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