pH Sensitive Erythrocyte-Derived Membrane for Acute Systemic Retention and Increased Infectivity of Coated Oncolytic Vaccinia Virus

Oncolytic viruses have emerged as a promising modality in cancer treatment given their high synergy with highly efficient immune checkpoint inhibitors. However, their potency is limited by their rapid in vivo clearance. To overcome this, we coated oncolytic vaccinia viruses (oVV) with erythrocyte-de...

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Detalles Bibliográficos
Autores principales: Samoranos, Kaelan T., Krisiewicz, Alexandra L., Karpinecz, Bianca C., Glover, Philip A., Gale, Trevor V., Chehadeh, Carla, Ashshan, Sheikh, Koya, Richard, Chung, Eddie Y., Lim, Han L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504069/
https://www.ncbi.nlm.nih.gov/pubmed/36145558
http://dx.doi.org/10.3390/pharmaceutics14091810

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