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Nanopore Detection Assisted DNA Information Processing

The deoxyribonucleotide (DNA) molecule is a stable carrier for large amounts of genetic information and provides an ideal storage medium for next-generation information processing technologies. Technologies that process DNA information, representing a cross-disciplinary integration of biology and co...

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Detalles Bibliográficos
Autores principales: Song, Zichen, Liang, Yuan, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504103/
https://www.ncbi.nlm.nih.gov/pubmed/36144924
http://dx.doi.org/10.3390/nano12183135
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author Song, Zichen
Liang, Yuan
Yang, Jing
author_facet Song, Zichen
Liang, Yuan
Yang, Jing
author_sort Song, Zichen
collection PubMed
description The deoxyribonucleotide (DNA) molecule is a stable carrier for large amounts of genetic information and provides an ideal storage medium for next-generation information processing technologies. Technologies that process DNA information, representing a cross-disciplinary integration of biology and computer techniques, have become attractive substitutes for technologies that process electronic information alone. The detailed applications of DNA technologies can be divided into three components: storage, computing, and self-assembly. The quality of DNA information processing relies on the accuracy of DNA reading. Nanopore detection allows researchers to accurately sequence nucleotides and is thus widely used to read DNA. In this paper, we introduce the principles and development history of nanopore detection and conduct a systematic review of recent developments and specific applications in DNA information processing involving nanopore detection and nanopore-based storage. We also discuss the potential of artificial intelligence in nanopore detection and DNA information processing. This work not only provides new avenues for future nanopore detection development, but also offers a foundation for the construction of more advanced DNA information processing technologies.
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spelling pubmed-95041032022-09-24 Nanopore Detection Assisted DNA Information Processing Song, Zichen Liang, Yuan Yang, Jing Nanomaterials (Basel) Review The deoxyribonucleotide (DNA) molecule is a stable carrier for large amounts of genetic information and provides an ideal storage medium for next-generation information processing technologies. Technologies that process DNA information, representing a cross-disciplinary integration of biology and computer techniques, have become attractive substitutes for technologies that process electronic information alone. The detailed applications of DNA technologies can be divided into three components: storage, computing, and self-assembly. The quality of DNA information processing relies on the accuracy of DNA reading. Nanopore detection allows researchers to accurately sequence nucleotides and is thus widely used to read DNA. In this paper, we introduce the principles and development history of nanopore detection and conduct a systematic review of recent developments and specific applications in DNA information processing involving nanopore detection and nanopore-based storage. We also discuss the potential of artificial intelligence in nanopore detection and DNA information processing. This work not only provides new avenues for future nanopore detection development, but also offers a foundation for the construction of more advanced DNA information processing technologies. MDPI 2022-09-09 /pmc/articles/PMC9504103/ /pubmed/36144924 http://dx.doi.org/10.3390/nano12183135 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Song, Zichen
Liang, Yuan
Yang, Jing
Nanopore Detection Assisted DNA Information Processing
title Nanopore Detection Assisted DNA Information Processing
title_full Nanopore Detection Assisted DNA Information Processing
title_fullStr Nanopore Detection Assisted DNA Information Processing
title_full_unstemmed Nanopore Detection Assisted DNA Information Processing
title_short Nanopore Detection Assisted DNA Information Processing
title_sort nanopore detection assisted dna information processing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504103/
https://www.ncbi.nlm.nih.gov/pubmed/36144924
http://dx.doi.org/10.3390/nano12183135
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AT liangyuan nanoporedetectionassisteddnainformationprocessing
AT yangjing nanoporedetectionassisteddnainformationprocessing