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Nanopore Detection Assisted DNA Information Processing
The deoxyribonucleotide (DNA) molecule is a stable carrier for large amounts of genetic information and provides an ideal storage medium for next-generation information processing technologies. Technologies that process DNA information, representing a cross-disciplinary integration of biology and co...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504103/ https://www.ncbi.nlm.nih.gov/pubmed/36144924 http://dx.doi.org/10.3390/nano12183135 |
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author | Song, Zichen Liang, Yuan Yang, Jing |
author_facet | Song, Zichen Liang, Yuan Yang, Jing |
author_sort | Song, Zichen |
collection | PubMed |
description | The deoxyribonucleotide (DNA) molecule is a stable carrier for large amounts of genetic information and provides an ideal storage medium for next-generation information processing technologies. Technologies that process DNA information, representing a cross-disciplinary integration of biology and computer techniques, have become attractive substitutes for technologies that process electronic information alone. The detailed applications of DNA technologies can be divided into three components: storage, computing, and self-assembly. The quality of DNA information processing relies on the accuracy of DNA reading. Nanopore detection allows researchers to accurately sequence nucleotides and is thus widely used to read DNA. In this paper, we introduce the principles and development history of nanopore detection and conduct a systematic review of recent developments and specific applications in DNA information processing involving nanopore detection and nanopore-based storage. We also discuss the potential of artificial intelligence in nanopore detection and DNA information processing. This work not only provides new avenues for future nanopore detection development, but also offers a foundation for the construction of more advanced DNA information processing technologies. |
format | Online Article Text |
id | pubmed-9504103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95041032022-09-24 Nanopore Detection Assisted DNA Information Processing Song, Zichen Liang, Yuan Yang, Jing Nanomaterials (Basel) Review The deoxyribonucleotide (DNA) molecule is a stable carrier for large amounts of genetic information and provides an ideal storage medium for next-generation information processing technologies. Technologies that process DNA information, representing a cross-disciplinary integration of biology and computer techniques, have become attractive substitutes for technologies that process electronic information alone. The detailed applications of DNA technologies can be divided into three components: storage, computing, and self-assembly. The quality of DNA information processing relies on the accuracy of DNA reading. Nanopore detection allows researchers to accurately sequence nucleotides and is thus widely used to read DNA. In this paper, we introduce the principles and development history of nanopore detection and conduct a systematic review of recent developments and specific applications in DNA information processing involving nanopore detection and nanopore-based storage. We also discuss the potential of artificial intelligence in nanopore detection and DNA information processing. This work not only provides new avenues for future nanopore detection development, but also offers a foundation for the construction of more advanced DNA information processing technologies. MDPI 2022-09-09 /pmc/articles/PMC9504103/ /pubmed/36144924 http://dx.doi.org/10.3390/nano12183135 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Song, Zichen Liang, Yuan Yang, Jing Nanopore Detection Assisted DNA Information Processing |
title | Nanopore Detection Assisted DNA Information Processing |
title_full | Nanopore Detection Assisted DNA Information Processing |
title_fullStr | Nanopore Detection Assisted DNA Information Processing |
title_full_unstemmed | Nanopore Detection Assisted DNA Information Processing |
title_short | Nanopore Detection Assisted DNA Information Processing |
title_sort | nanopore detection assisted dna information processing |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504103/ https://www.ncbi.nlm.nih.gov/pubmed/36144924 http://dx.doi.org/10.3390/nano12183135 |
work_keys_str_mv | AT songzichen nanoporedetectionassisteddnainformationprocessing AT liangyuan nanoporedetectionassisteddnainformationprocessing AT yangjing nanoporedetectionassisteddnainformationprocessing |