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Synthesis of Novel N(4)-Hydrocytidine Analogs as Potential Anti-SARS-CoV-2 Agents

Coronavirus disease 2019 (COVID-19) is an emerging global pandemic with severe morbidity and mortality caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Molnupiravir, an ester prodrug form of N(4)-hydroxycytidine (NHC), was recently emergency-use approved for the treatment...

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Detalles Bibliográficos
Autores principales: Amblard, Franck, LeCher, Julia C., De, Ramyani, Goh, Shu Ling, Li, Chengwei, Kasthuri, Mahesh, Biteau, Nicolas, Zhou, Longhu, Tber, Zahira, Downs-Bowen, Jessica, Zandi, Keivan, Schinazi, Raymond F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504122/
https://www.ncbi.nlm.nih.gov/pubmed/36145365
http://dx.doi.org/10.3390/ph15091144

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