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Chidamide plus Tyrosine Kinase Inhibitor Remodel the Tumor Immune Microenvironment and Reduce Tumor Progression When Combined with Immune Checkpoint Inhibitor in Naïve and Anti-PD-1 Resistant CT26-Bearing Mice
Combined inhibition of vascular endothelial growth factor receptor (VEGFR) and the programmed cell death protein 1 (PD-1) pathways has shown efficacy in multiple cancers; however, the clinical outcomes show limited benefits and the unmet clinical needs still remain and require improvement in efficac...
Autores principales: | Chen, Jia-Shiong, Hsieh, Yi-Chien, Chou, Cheng-Han, Wu, Yi-Hong, Yang, Mu-Hsuan, Chu, Sz-Hao, Chao, Ye-Su, Chen, Chia-Nan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504159/ https://www.ncbi.nlm.nih.gov/pubmed/36142591 http://dx.doi.org/10.3390/ijms231810677 |
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