Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa via an In Vitro Model

Modulation of drug transporter activity at mucosal sites of HIV-1 transmission may be exploited to optimize retention of therapeutic antiretroviral drug concentrations at target submucosal CD4+ T cells. Previously, we showed that darunavir was a substrate for the P-glycoprotein efflux drug transport...

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Detalles Bibliográficos
Autores principales: Carserides, Constandinos, Smith, Kieron, Zinicola, Marta, Kumar, Abhinav, Swedrowska, Magda, Scala, Carlo, Cameron, Gary, Riches, Zoe, Iannelli, Francesco, Pozzi, Gianni, Hold, Georgina L., Forbes, Ben, Kelly, Charles, Hijazi, Karolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504208/
https://www.ncbi.nlm.nih.gov/pubmed/36145684
http://dx.doi.org/10.3390/pharmaceutics14091938

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