Broad-Spectrum Small-Molecule Inhibitors of the SARS-CoV-2 Spike—ACE2 Protein–Protein Interaction from a Chemical Space of Privileged Protein Binders

Therapeutically useful small-molecule inhibitors (SMIs) of protein–protein interactions (PPIs) initiating the cell attachment and entry of viruses could provide novel alternative antivirals that act via mechanisms similar to that of neutralizing antibodies but retain the advantages of small-molecule...

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Detalles Bibliográficos
Autores principales: Chuang, Sung-Ting, Buchwald, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504289/
https://www.ncbi.nlm.nih.gov/pubmed/36145305
http://dx.doi.org/10.3390/ph15091084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504289/
https://www.ncbi.nlm.nih.gov/pubmed/36145305
http://dx.doi.org/10.3390/ph15091084

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