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Piperine as Therapeutic Agent in Paracetamol-Induced Hepatotoxicity in Mice

High doses of paracetamol (APAP) can cause irreversible liver damage. Piperine (P) inhibits cytochrome P450, which is involved in the metabolism of various xenobiotics, including paracetamol. We evaluated the hepatoprotective effects of piperine with or without N-acetylcysteine (NAC) in APAP-induced...

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Detalles Bibliográficos
Autores principales:	Coelho, Aline Meireles, Queiroz, Isabela Ferreira, Perucci, Luiza Oliveira, de Souza, Melina Oliveira, Lima, Wanderson Geraldo, Talvani, André, Costa, Daniela Caldeira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504321/ https://www.ncbi.nlm.nih.gov/pubmed/36145547 http://dx.doi.org/10.3390/pharmaceutics14091800

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