Cargando…

Therapeutic Effects of Saponins for the Prevention and Treatment of Cancer by Ameliorating Inflammation and Angiogenesis and Inducing Antioxidant and Apoptotic Effects in Human Cells

Saponins are natural compounds found in plants and have a diverse range of applications. However, the therapeutic potential of saponins in regulating cytotoxicity, angiogenesis, and inflammation in mammalian cells is yet to be explored. Here, we investigated the therapeutic effects of saponins from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Muhammad Imran, Karima, Gul, Khan, Muhammad Zubair, Shin, Jin Hyuk, Kim, Jong Deog
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504392/ https://www.ncbi.nlm.nih.gov/pubmed/36142578 http://dx.doi.org/10.3390/ijms231810665

Ejemplares similares

Correction: Khan et al. Therapeutic Effects of Saponins for the Prevention and Treatment of Cancer by Ameliorating Inflammation and Angiogenesis and Inducing Antioxidant and Apoptotic Effects in Human Cells. Int. J. Mol. Sci. 2022, 23, 10665
por: Khan, Muhammad Imran, et al.
Publicado: (2023)

Neuroprotective Effects of Green Tea Seed Isolated Saponin Due to the Amelioration of Tauopathy and Alleviation of Neuroinflammation: A Therapeutic Approach to Alzheimer’s Disease
por: Khan, Muhammad Imran, et al.
Publicado: (2022)

Stem cells-derived exosomes alleviate neurodegeneration and Alzheimer’s pathogenesis by ameliorating neuroinflamation, and regulating the associated molecular pathways
por: Khan, Muhammad Imran, et al.
Publicado: (2023)

Crude microcystins extracted from Microcystis aeruginosa exert anti-obesity effects by downregulating angiogenesis and adipogenesis related signaling molecules in HUVEC and 3 T3-L1 cells
por: Khan, Muhammad Imran, et al.
Publicado: (2019)

Green Tea Seed Isolated Saponins Exerts Antibacterial Effects against Various Strains of Gram Positive and Gram Negative Bacteria, a Comprehensive Study In Vitro and In Vivo
por: Khan, Muhammad Imran, et al.
Publicado: (2018)

Pharmacological Approaches to Attenuate Inflammation and Obesity with Natural Products Formulations by Regulating the Associated Promoting Molecular Signaling Pathways
por: Khan, Muhammad Imran, et al.
Publicado: (2021)

Green Tea Seed Isolated Theasaponin E1 Ameliorates AD Promoting Neurotoxic Pathogenesis by Attenuating Aβ Peptide Levels in SweAPP N2a Cells
por: Khan, Muhammad Imran, et al.
Publicado: (2020)

The promising future of microalgae: current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products
por: Khan, Muhammad Imran, et al.
Publicado: (2018)

Antiobesity, hypolipidemic, antioxidant and hepatoprotective effects of Achyranthes aspera seed saponins in high cholesterol fed albino rats
por: Khan, Naveed, et al.
Publicado: (2015)

Pretreatment optimization of the biomass of Microcystis aeruginosa for efficient bioethanol production
por: Khan, Muhammad Imran, et al.
Publicado: (2017)

Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions
por: Ikram, Muhammad, et al.
Publicado: (2021)

Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L.: potential effectiveness in Alzheimer’s and other neurological disorders
por: Kamal, Zul, et al.
Publicado: (2015)

Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L
por: Ayaz, Muhammad, et al.
Publicado: (2014)

Rhizoma Paridis saponins ameliorates hepatic fibrosis in rats by downregulating expression of angiogenesis-associated growth factors
por: Han, Yanquan, et al.
Publicado: (2019)

Melatonin Ameliorates Thermotolerance in Soybean Seedling through Balancing Redox Homeostasis and Modulating Antioxidant Defense, Phytohormones and Polyamines Biosynthesis
por: Imran, Muhammad, et al.
Publicado: (2021)

Anthocyanins from Cornus kousa ethanolic extract attenuate obesity in association with anti-angiogenic activities in 3T3-L1 cells by down-regulating adipogeneses and lipogenesis
por: Khan, Muhammad Imran, et al.
Publicado: (2018)

Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
por: Nadeem, Muhammad Shahid, et al.
Publicado: (2021)

In-vitro Pro Apoptotic Effect of Crude Saponin from Ophiocoma erinaceus against Cervical Cancer
por: Amini, Elaheh, et al.
Publicado: (2017)

Ginseng saponins and the treatment of osteoporosis: mini literature review
por: Siddiqi, Muhammad Hanif, et al.
Publicado: (2013)

Chemical Characterization and Ameliorating Effect of Centratherum anthelminticum Extract against Polycystic Ovary Syndrome in Wistar Rats
por: Shoaib, Moonis, et al.
Publicado: (2023)

Panax Notoginseng Saponins Ameliorate Aβ-Mediated Neurotoxicity in C. elegans through Antioxidant Activities
por: Zhou, Ling, et al.
Publicado: (2019)

Effect of microcapsules of chia oil on Ω-3 fatty acids, antioxidant characteristics and oxidative stability of butter
por: Ullah, Rahman, et al.
Publicado: (2020)

Therapeutic Effect of Total Ginseng Saponin on Skin Wound Healing
por: Kim, Young Soo, et al.
Publicado: (2011)

Intermittent fasting positively modulates human gut microbial diversity and ameliorates blood lipid profile
por: Khan, Muhammad Nadeem, et al.
Publicado: (2022)

Antiproliferative and Apoptotic Effects of Graphene Oxide @AlFu MOF Based Saponin Natural Product on OSCC Line
por: Mousavi, Seyyed Mojtaba, et al.
Publicado: (2022)

Evaluation of phytochemicals, antioxidant activity and amelioration of pulmonary fibrosis with Phyllanthus emblica leaves
por: Tahir, Irsa, et al.
Publicado: (2016)

Tyrosinase Inhibitory Effects and Antioxidative Activities of Saponins from Xanthoceras Sorbifolia Nutshell
por: Zhang, Hongmei, et al.
Publicado: (2013)

Triglyceride, fatty acid profile and antioxidant characteristics of low melting point fractions of Buffalo Milk fat
por: Khan, Imran Taj, et al.
Publicado: (2019)

Attenuation and Production of the Amphotericin B-Resistant Leishmania tropica Strain
por: Khan, Imran, et al.
Publicado: (2016)

Young man with severe metabolic acidosis after transformer oil ingestion: a case report
por: Khan, Farah Gul, et al.
Publicado: (2018)

Prevention Effect of Protopanaxadiol-Type Saponins Saponins and Protopanaxatriol-Type Saponins on Myelosuppression Mice Induced by Cyclophosphamide
por: Zhang, He, et al.
Publicado: (2022)

Extraction of saponins and toxicological profile of Teucrium stocksianum boiss extracts collected from District Swat, Pakistan
por: Shah, Syed Muhammad Mukarram, et al.
Publicado: (2014)

The Apoptotic Effect of D Rhamnose β-Hederin, a Novel Oleanane-Type Triterpenoid Saponin on Breast Cancer Cells
por: Cheng, Lin, et al.
Publicado: (2014)

Antioxidant properties of Milk and dairy products: a comprehensive review of the current knowledge
por: Khan, Imran Taj, et al.
Publicado: (2019)

Impact of AKT1 Polymorphism on DNA Damage, BTG2 Expression, and Risk of Colorectal Cancer Development
por: Zubair, Hina, et al.
Publicado: (2022)

Crude Saponin from Platycodon grandiflorum Attenuates Aβ-Induced Neurotoxicity via Antioxidant, Anti-Inflammatory and Anti-Apoptotic Signaling Pathways
por: Ji, Yun-Jeong, et al.
Publicado: (2021)

Antioxidant, Anti-Aging and Organ Protective Effects of Total Saponins from Aralia taibaiensis
por: Li, Huan, et al.
Publicado: (2021)

Bioactive Steroids and Saponins of the Genus Trillium
por: Ur Rahman, Shafiq, et al.
Publicado: (2017)

Lipolysis and antioxidant properties of cow and buffalo cheddar cheese in accelerated ripening
por: Batool, Maryam, et al.
Publicado: (2018)

Antioxidant capacity and fatty acids characterization of heat treated cow and buffalo milk
por: Khan, Imran Taj, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9evlg451ar9d2v88e11hglt0q1