Identification of a Potential Inhibitor (MCULE-8777613195-0-12) of New Delhi Metallo-β-Lactamase-1 (NDM-1) Using In Silico and In Vitro Approaches

New Delhi metallo-β-lactamase-1 (NDM-1), expressed in different Gram-negative bacteria, is a versatile enzyme capable of hydrolyzing β-lactam rings containing antibiotics such as penicillins, cephalosporins, and even carbapenems. Multidrug resistance in bacteria mediated by NDM-1 is an emerging thre...

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Detalles Bibliográficos
Autores principales: Muteeb, Ghazala, Rehman, Md Tabish, AlAjmi, Mohamed F., Aatif, Mohammad, Farhan, Mohd, Shafi, Sheeba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504514/
https://www.ncbi.nlm.nih.gov/pubmed/36144666
http://dx.doi.org/10.3390/molecules27185930

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