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Stability Study, Quantification Method and Pharmacokinetics Investigation of a Coumarin–Monoterpene Conjugate Possessing Antiviral Properties against Respiratory Syncytial Virus
The stability of a new coumarin derivative, agent K-142, bearing α-pinene residue and possessing antiviral activity against respiratory syncytial virus (RSV) was studied in whole mice blood in vitro, and a method for its quantification in this matrix was developed and validated. The sample preparati...
Autores principales: | Nemolochnova, Arina G., Rogachev, Artem D., Salnikova, Olga P., Khomenko, Tatyana M., Volcho, Konstantin P., Yarovaya, Olga I., Fatianova, Alina V., Pokrovsky, Andrey G., Salakhutdinov, Nariman F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504583/ https://www.ncbi.nlm.nih.gov/pubmed/36145379 http://dx.doi.org/10.3390/ph15091158 |
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