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Applications of the Novel Quantitative Pharmacophore Activity Relationship Method QPhAR in Virtual Screening and Lead-Optimisation

Pharmacophores are an established concept for the modelling of ligand–receptor interactions based on the abstract representations of stereoelectronic molecular features. They became widely popular as filters for the fast virtual screening of large compound libraries. A lot of effort has been put int...

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Detalles Bibliográficos
Autores principales:	Kohlbacher, Stefan Michael, Schmid, Matthias, Seidel, Thomas, Langer, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504690/ https://www.ncbi.nlm.nih.gov/pubmed/36145343 http://dx.doi.org/10.3390/ph15091122

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