Plasma Small Extracellular Vesicle Cathepsin D Dysregulation in GRN/C9orf72 and Sporadic Frontotemporal Lobar Degeneration

Emerging data suggest the roles of endo-lysosomal dysfunctions in frontotemporal lobar degeneration (FTLD) and in other dementias. Cathepsin D is one of the major lysosomal proteases, mediating the degradation of unfolded protein aggregates. In this retrospective study, we investigated cathepsin D l...

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Detalles Bibliográficos
Autores principales: Bellini, Sonia, Saraceno, Claudia, Benussi, Luisa, Geviti, Andrea, Longobardi, Antonio, Nicsanu, Roland, Cimini, Sara, Ricci, Martina, Canafoglia, Laura, Coppola, Cinzia, Puoti, Gianfranco, Binetti, Giuliano, Rossi, Giacomina, Ghidoni, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504770/
https://www.ncbi.nlm.nih.gov/pubmed/36142612
http://dx.doi.org/10.3390/ijms231810693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504770/
https://www.ncbi.nlm.nih.gov/pubmed/36142612
http://dx.doi.org/10.3390/ijms231810693

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