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Optical Redox Imaging of Ex Vivo Hippocampal Tissue Reveals Age-Dependent Alterations in the 5XFAD Mouse Model of Alzheimer’s Disease

A substantial decline in nicotinamide adenine dinucleotide (NAD) has been reported in brain tissue homogenates or neurons isolated from Alzheimer’s disease (AD) models. NAD, together with flavin adenine dinucleotide (FAD), critically supports energy metabolism and maintains mitochondrial redox homeo...

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Detalles Bibliográficos
Autores principales:	Xu, He N., Gourmaud, Sarah, Podsednik, Allison, Li, Xiaofan, Zhao, Huaqing, Jensen, Frances E., Talos, Delia M., Li, Lin Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504813/ https://www.ncbi.nlm.nih.gov/pubmed/36144191 http://dx.doi.org/10.3390/metabo12090786

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