In Vitro and In Silico Analyses of New Cinnamid and Rosmarinic Acid-Derived Compounds Biosynthesized in Escherichia coli as Leishmania amazonensis Arginase Inhibitors

Arginase is a metalloenzyme that plays a central role in Leishmania infections. Previously, rosmarinic and caffeic acids were described as antileishmanial agents and as Leishmania amazonensis arginase inhibitors. Here, we describe the inhibition of arginase in L. amazonensis by rosmarinic acid analo...

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Detalles Bibliográficos
Autores principales: Come, Julio Abel Alfredo dos Santos Simone, Zhuang, Yibin, Li, Tianzhen, Brogi, Simone, Gemma, Sandra, Liu, Tao, da Silva, Edson Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504950/
https://www.ncbi.nlm.nih.gov/pubmed/36145452
http://dx.doi.org/10.3390/pathogens11091020

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