Cargando…

Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer

Micromixers are one of the critical components in microfluidic devices. They significantly affect the efficiency and sensitivity of microfluidics-based lab-on-a-chip systems. This study introduces an efficient micromixer with a simple geometrical feature that enables easy incorporation in a microcha...

Descripción completa

Detalles Bibliográficos
Autores principales: Natsuhara, Daigo, Saito, Ryogo, Okamoto, Shunya, Nagai, Moeto, Shibata, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504961/
https://www.ncbi.nlm.nih.gov/pubmed/36144009
http://dx.doi.org/10.3390/mi13091386
_version_ 1784796351562776576
author Natsuhara, Daigo
Saito, Ryogo
Okamoto, Shunya
Nagai, Moeto
Shibata, Takayuki
author_facet Natsuhara, Daigo
Saito, Ryogo
Okamoto, Shunya
Nagai, Moeto
Shibata, Takayuki
author_sort Natsuhara, Daigo
collection PubMed
description Micromixers are one of the critical components in microfluidic devices. They significantly affect the efficiency and sensitivity of microfluidics-based lab-on-a-chip systems. This study introduces an efficient micromixer with a simple geometrical feature that enables easy incorporation in a microchannel network without compromising the original design of microfluidic devices. The study proposes a newly designed planar passive micromixer, termed a planar asymmetric contraction-and-expansion (P-ACE) micromixer, with asymmetric vertical obstacle structures. Numerical simulation and experimental investigation revealed that the optimally designed P-ACE micromixer exhibited a high mixing efficiency of 80% or more within a microchannel length of 10 mm over a wide range of Reynolds numbers (0.13 ≤ Re ≤ 13), eventually attaining approximately 90% mixing efficiency within a 20 mm microchannel length. The highly asymmetric geometric features of the P-ACE micromixers enhance mixing because of their synergistic effects. The flow velocities and directions of the two fluids change differently while alternately crossing the longitudinal centerline of the microchannel, with the obstacle structures asymmetrically arranged on both sidewalls of the rectangular microchannel. This flow behavior increases the interfacial contact area between the two fluids, thus promoting effective mixing in the P-ACE micromixer. Further, the pressure drops in the P-ACE micromixers were experimentally investigated and compared with those in a serpentine micromixer with a perfectly symmetric mixing unit.
format Online
Article
Text
id pubmed-9504961
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95049612022-09-24 Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer Natsuhara, Daigo Saito, Ryogo Okamoto, Shunya Nagai, Moeto Shibata, Takayuki Micromachines (Basel) Article Micromixers are one of the critical components in microfluidic devices. They significantly affect the efficiency and sensitivity of microfluidics-based lab-on-a-chip systems. This study introduces an efficient micromixer with a simple geometrical feature that enables easy incorporation in a microchannel network without compromising the original design of microfluidic devices. The study proposes a newly designed planar passive micromixer, termed a planar asymmetric contraction-and-expansion (P-ACE) micromixer, with asymmetric vertical obstacle structures. Numerical simulation and experimental investigation revealed that the optimally designed P-ACE micromixer exhibited a high mixing efficiency of 80% or more within a microchannel length of 10 mm over a wide range of Reynolds numbers (0.13 ≤ Re ≤ 13), eventually attaining approximately 90% mixing efficiency within a 20 mm microchannel length. The highly asymmetric geometric features of the P-ACE micromixers enhance mixing because of their synergistic effects. The flow velocities and directions of the two fluids change differently while alternately crossing the longitudinal centerline of the microchannel, with the obstacle structures asymmetrically arranged on both sidewalls of the rectangular microchannel. This flow behavior increases the interfacial contact area between the two fluids, thus promoting effective mixing in the P-ACE micromixer. Further, the pressure drops in the P-ACE micromixers were experimentally investigated and compared with those in a serpentine micromixer with a perfectly symmetric mixing unit. MDPI 2022-08-25 /pmc/articles/PMC9504961/ /pubmed/36144009 http://dx.doi.org/10.3390/mi13091386 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Natsuhara, Daigo
Saito, Ryogo
Okamoto, Shunya
Nagai, Moeto
Shibata, Takayuki
Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer
title Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer
title_full Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer
title_fullStr Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer
title_full_unstemmed Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer
title_short Mixing Performance of a Planar Asymmetric Contraction-and-Expansion Micromixer
title_sort mixing performance of a planar asymmetric contraction-and-expansion micromixer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504961/
https://www.ncbi.nlm.nih.gov/pubmed/36144009
http://dx.doi.org/10.3390/mi13091386
work_keys_str_mv AT natsuharadaigo mixingperformanceofaplanarasymmetriccontractionandexpansionmicromixer
AT saitoryogo mixingperformanceofaplanarasymmetriccontractionandexpansionmicromixer
AT okamotoshunya mixingperformanceofaplanarasymmetriccontractionandexpansionmicromixer
AT nagaimoeto mixingperformanceofaplanarasymmetriccontractionandexpansionmicromixer
AT shibatatakayuki mixingperformanceofaplanarasymmetriccontractionandexpansionmicromixer