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Recombinant Mammalian Prions: The “Correctly” Misfolded Prion Protein Conformers

Generating a prion with exogenously produced recombinant prion protein is widely accepted as the ultimate proof of the prion hypothesis. Over the years, a plethora of misfolded recPrP conformers have been generated, but despite their seeding capability, many of them have failed to elicit a fatal neu...

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Detalles Bibliográficos
Autores principales: Ma, Jiyan, Zhang, Jingjing, Yan, Runchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504972/
https://www.ncbi.nlm.nih.gov/pubmed/36146746
http://dx.doi.org/10.3390/v14091940