Cargando…
Recombinant Mammalian Prions: The “Correctly” Misfolded Prion Protein Conformers
Generating a prion with exogenously produced recombinant prion protein is widely accepted as the ultimate proof of the prion hypothesis. Over the years, a plethora of misfolded recPrP conformers have been generated, but despite their seeding capability, many of them have failed to elicit a fatal neu...
Autores principales: | Ma, Jiyan, Zhang, Jingjing, Yan, Runchuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504972/ https://www.ncbi.nlm.nih.gov/pubmed/36146746 http://dx.doi.org/10.3390/v14091940 |
Ejemplares similares
-
Prion Protein Misfolding, Strains, and Neurotoxicity: An Update from Studies on Mammalian Prions
por: Poggiolini, Ilaria, et al.
Publicado: (2013) -
Prion Protein Misfolding
por: Kupfer, L, et al.
Publicado: (2009) -
Differential Accumulation of Misfolded Prion Strains in Natural Hosts of Prion Diseases
por: Lambert, Zoe J., et al.
Publicado: (2021) -
Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma
por: Daus, Martin L.
Publicado: (2016) -
The protease-sensitive N-terminal polybasic region of prion protein modulates its conversion to the pathogenic prion conformer
por: Zhang, Xiangyi, et al.
Publicado: (2021)