Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity

Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities. Among them, compounds 6a/6c/7g/19a/19b exhibited excellent androgen receptor antagonistic activity, which was consistent with...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Longjun, Zhou, Yan, Yang, Dehua, Wang, Ming-Wei, Lu, Wei, Jin, Jiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505067/
https://www.ncbi.nlm.nih.gov/pubmed/36144603
http://dx.doi.org/10.3390/molecules27185867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505067/
https://www.ncbi.nlm.nih.gov/pubmed/36144603
http://dx.doi.org/10.3390/molecules27185867

Ejemplares similares