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Structure of Lacticaseicin 30 and Its Engineered Variants Revealed an Interplay between the N-Terminal and C-Terminal Regions in the Activity against Gram-Negative Bacteria

Lacticaseicin 30 is one of the five bacteriocins produced by the Gram-positive Lacticaseibacillus paracasei CNCM I-5369. This 111 amino acid bacteriocin is noteworthy for being active against Gram-negative bacilli including Escherichia coli strains resistant to colistin. Prediction of the lacticasei...

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Detalles Bibliográficos
Autores principales:	Madi-Moussa, Désiré, Deracinois, Barbara, Teiar, Radja, Li, Yanyan, Mihasan, Marius, Flahaut, Christophe, Rebuffat, Sylvie, Coucheney, Françoise, Drider, Djamel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505257/ https://www.ncbi.nlm.nih.gov/pubmed/36145669 http://dx.doi.org/10.3390/pharmaceutics14091921

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