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Lung-Targeted Delivery of Cepharanthine by an Erythrocyte-Anchoring Strategy for the Treatment of Acute Lung Injury

As one of the most frequent complications of critical illness, acute lung injury (ALI) carries a high risk of clinical morbidity and mortality. Cepharanthine (CPA) has significant anti-inflammatory activity, however, due to poor water solubility, low bioavailability, and short half-life, it fails to...

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Detalles Bibliográficos
Autores principales: Zheng, Jinpeng, Lu, Caihong, Yang, Meiyan, Sun, Jiejie, Zhang, Jinbang, Meng, Yuanyuan, Wang, Yuli, Li, Zhiping, Yang, Yang, Gong, Wei, Gao, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505324/
https://www.ncbi.nlm.nih.gov/pubmed/36145566
http://dx.doi.org/10.3390/pharmaceutics14091820