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FLU-v, a Broad-Spectrum Influenza Vaccine, Induces Cross-Reactive Cellular Immune Responses in Humans Measured by Dual IFN-γ and Granzyme B ELISpot Assay
Previous reports demonstrated that FLU-v, a peptide-based broad-spectrum influenza vaccine candidate, induced antibody and cellular immune responses in humans. Here, we evaluate cellular effector functions and cross-reactivity. PBMC sampled pre- (day 0) and post-vaccination (days 42 and 180) from va...
Autores principales: | Oftung, Fredrik, Næss, Lisbeth M., Laake, Ida, Stoloff, Gregory, Pleguezuelos, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505334/ https://www.ncbi.nlm.nih.gov/pubmed/36146606 http://dx.doi.org/10.3390/vaccines10091528 |
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