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Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity

Bilirubin is a heme catabolite and Ugt1a1 is the only enzyme involved in the biological elimination of bilirubin. Partially functional or non-functional Ugt1a1 may result in neuronal damage and death due to the accumulation of unconjugated bilirubin in the brain. The understanding of the role of alt...

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Detalles Bibliográficos
Autores principales:	Banerjee, Bhaswati, Olajide, Olayemi Joseph, Bortolussi, Giulia, Muro, Andrés F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505366/ https://www.ncbi.nlm.nih.gov/pubmed/36142606 http://dx.doi.org/10.3390/ijms231810703

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