Cargando…
Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex
Neuroinflammation has a major role in several brain disorders including Alzheimer’s disease (AD), yet at present there are no effective anti-neuroinflammatory therapeutics available. Copper(II) complexes of bis(thiosemicarbazones) (Cu(II)(gtsm) and Cu(II)(atsm)) have broad therapeutic actions in pre...
Autores principales: | Choo, Xin Yi, McInnes, Lachlan E., Grubman, Alexandra, Wasielewska, Joanna M., Belaya, Irina, Burrows, Emma, Quek, Hazel, Martín, Jorge Cañas, Loppi, Sanna, Sorvari, Annika, Rait, Dzhessi, Powell, Andrew, Duncan, Clare, Liddell, Jeffrey R., Tanila, Heikki, Polo, Jose M., Malm, Tarja, Kanninen, Katja M., Donnelly, Paul S., White, Anthony R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505367/ https://www.ncbi.nlm.nih.gov/pubmed/36142627 http://dx.doi.org/10.3390/ijms231810722 |
Ejemplares similares
-
Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer’s disease
por: Belaya, Irina, et al.
Publicado: (2020) -
Synthesis, Characterization and Biological Evaluation of Metal Adamantyl 2-Pyridylhydrazone Complexes
por: Shehadi, Ihsan A., et al.
Publicado: (2020) -
Cu(II)(atsm) Attenuates Neuroinflammation
por: Choo, Xin Yi, et al.
Publicado: (2018) -
Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration
por: Abdalkader, Moataz, et al.
Publicado: (2018) -
Regular Physical Exercise Modulates Iron Homeostasis in the 5xFAD Mouse Model of Alzheimer’s Disease
por: Belaya, Irina, et al.
Publicado: (2021)