Preparation of Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDS) by Co-Extrusion of Liquid SNEDDS and Polymeric Carriers—A New and Promising Formulation Approach to Improve the Solubility of Poorly Water-Soluble Drugs

The present study focused on a new formulation approach to improving the solubility of drugs with poor aqueous solubility. A hot melt extrusion (HME) process was applied to prepare drug-loaded solid self-nanoemulsifying drug delivery systems (S-SNEDDS) by co-extrusion of liquid SNEDDS (L-SNEDDS) and...

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Detalles Bibliográficos
Autores principales: Schmied, Fabian-Pascal, Bernhardt, Alexander, Klein, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505398/
https://www.ncbi.nlm.nih.gov/pubmed/36145356
http://dx.doi.org/10.3390/ph15091135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505398/
https://www.ncbi.nlm.nih.gov/pubmed/36145356
http://dx.doi.org/10.3390/ph15091135

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