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Optimization of a Protocol for Protein Extraction from Calcified Aortic Valves for Proteomics Applications: Development of a Standard Operating Procedure

The comprehension of the pathophysiological mechanisms, the identification of druggable targets, and putative biomarkers for aortic valve stenosis can be pursued through holistic approaches such as proteomics. However, tissue homogenization and protein extraction are made difficult by tissue calcifi...

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Detalles Bibliográficos
Autores principales:	Trindade, Fábio, Ferreira, Ana F., Saraiva, Francisca, Martins, Diana, Mendes, Vera M., Sousa, Carla, Gavina, Cristina, Leite-Moreira, Adelino, Manadas, Bruno, Falcão-Pires, Inês, Vitorino, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505568/ https://www.ncbi.nlm.nih.gov/pubmed/36136308 http://dx.doi.org/10.3390/proteomes10030030

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