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A New Strategy for Efficient Screening and Identification of Monoclonal Antibodies against Oncogenic Avian Herpesvirus Utilizing CRISPR/Cas9-Based Gene-Editing Technology
Marek’s disease virus (MDV) is an important oncogenic α-herpesvirus that induces Marek’s disease (MD), characterized by severe immunosuppression and rapid-onset T-cell lymphomas in its natural chicken hosts. Historically, MD is regarded as an ideal biomedical model for studying virally induced cance...
Autores principales: | Teng, Man, Zhou, Zi-Yu, Yao, Yongxiu, Nair, Venugopal, Zhang, Gai-Ping, Luo, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505574/ https://www.ncbi.nlm.nih.gov/pubmed/36146851 http://dx.doi.org/10.3390/v14092045 |
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