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Intragenic L1 Insertion: One Possibility of Brain Disorder

Long interspersed nuclear element 1 (LINE1, L1) is a retrotransposon comprising ~17% of the human genome. A subset of L1s maintains the potential to mobilize and alter the genomic landscape, consequently contributing to the change in genome integrity and gene expression. L1 retrotransposition occurs...

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Detalles Bibliográficos
Autores principales: Son, Ji-Hoon, Do, Hyunsu, Han, Jinju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505610/
https://www.ncbi.nlm.nih.gov/pubmed/36143463
http://dx.doi.org/10.3390/life12091425

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