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Anti-Inflammatory Therapy for Temporomandibular Joint Osteoarthritis Using mRNA Medicine Encoding Interleukin-1 Receptor Antagonist

Messenger RNA (mRNA) is an emerging drug modality for protein replacement therapy. As mRNA efficiently provides protein expression in post-mitotic cells without the risk of insertional mutagenesis, direct delivery of mRNA can be applied, not only as an alternative to gene therapy, but also for vario...

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Detalles Bibliográficos
Autores principales: Deng, Jia, Fukushima, Yuta, Nozaki, Kosuke, Nakanishi, Hideyuki, Yada, Erica, Terai, Yuki, Fueki, Kenji, Itaka, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505648/
https://www.ncbi.nlm.nih.gov/pubmed/36145533
http://dx.doi.org/10.3390/pharmaceutics14091785