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Anti-Inflammatory Therapy for Temporomandibular Joint Osteoarthritis Using mRNA Medicine Encoding Interleukin-1 Receptor Antagonist
Messenger RNA (mRNA) is an emerging drug modality for protein replacement therapy. As mRNA efficiently provides protein expression in post-mitotic cells without the risk of insertional mutagenesis, direct delivery of mRNA can be applied, not only as an alternative to gene therapy, but also for vario...
Autores principales: | Deng, Jia, Fukushima, Yuta, Nozaki, Kosuke, Nakanishi, Hideyuki, Yada, Erica, Terai, Yuki, Fueki, Kenji, Itaka, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505648/ https://www.ncbi.nlm.nih.gov/pubmed/36145533 http://dx.doi.org/10.3390/pharmaceutics14091785 |
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