Cargando…

PARK7 deficiency inhibits fatty acid β‐oxidation via PTEN to delay liver regeneration after hepatectomy

BACKGROUND & AIMS: Transient regeneration–associated steatosis (TRAS) is a process of temporary hepatic lipid accumulation and is essential for liver regeneration by providing energy generated from fatty acid β‐oxidation, but the regulatory mechanism underlying TRAS remains unknown. Parkinsonism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Xiaoye, Wen, Yankai, Jiao, Junzhe, Zhao, Jie, Sun, Xuehua, Wang, Fang, Gao, Yueqiu, Tan, Weifeng, Xia, Qiang, Wu, Hailong, Kong, Xiaoni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505755/ https://www.ncbi.nlm.nih.gov/pubmed/36149763 http://dx.doi.org/10.1002/ctm2.1061

Ejemplares similares

Defective Initiation of Liver Regeneration in Osteopontin-Deficient Mice after Partial Hepatectomy due to Insufficient Activation of IL-6/Stat3 Pathway
por: Wen, Yankai, et al.
Publicado: (2015)

DJ-1 Deficiency in Hepatocytes Improves Liver Ischemia-Reperfusion Injury by Enhancing Mitophagy
por: Xu, Min, et al.
Publicado: (2021)

Deficiency of DJ-1 Ameliorates Liver Fibrosis through Inhibition of Hepatic ROS Production and Inflammation
por: Yu, Yingxue, et al.
Publicado: (2016)

Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response
por: Wang, Bingrui, et al.
Publicado: (2021)

Non-metabolic role of UCK2 links EGFR-AKT pathway activation to metastasis enhancement in hepatocellular carcinoma
por: Cai, Jie, et al.
Publicado: (2020)

DJ-1 Deficiency Protects Hepatic Steatosis by Enhancing Fatty Acid Oxidation in Mice
por: Xu, Min, et al.
Publicado: (2018)

Liver Regeneration in Chronic Liver Injuries: Basic and Clinical Applications Focusing on Macrophages and Natural Killer Cells
por: Qian, Yihan, et al.
Publicado: (2022)

Prognostic values of a novel multi-mRNA signature for predicting relapse of cholangiocarcinoma
por: Guo, Han, et al.
Publicado: (2020)

Electroacupuncture Pretreatment at Zusanli (ST36) Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice by Reducing Oxidative Stress via Activating Vagus Nerve-Dependent Nrf2 Pathway
por: Jiang, Haochen, et al.
Publicado: (2023)

Systematic elucidation of the mechanism of Jingyin granule in the treatment of Novel Coronavirus (COVID-19) Pneumonia via Network Pharmacology
por: Wang, Bingrui, et al.
Publicado: (2021)

Application of herbs and active ingredients ameliorate non-alcoholic fatty liver disease under the guidance of traditional Chinese medicine
por: Zhou, Zhijia, et al.
Publicado: (2022)

Methyl Diet Enhanced Sepsis-Induced Mortality Through Altering Gut Microbiota
por: Yu, Chang, et al.
Publicado: (2021)

Modulation of liver regeneration via myeloid PTEN deficiency
por: Ma, Wen-Tao, et al.
Publicado: (2017)

Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism
por: Zhi, Shang, et al.
Publicado: (2022)

Antibiotics enhancing drug-induced liver injury assessed for causality using Roussel Uclaf Causality Assessment Method: Emerging role of gut microbiota dysbiosis
por: Fu, Lihong, et al.
Publicado: (2022)

Interleukin-22 protects from endotoxemia by inducing suppressive F4/80(+)Ly6G(hi)Ly6C(hi) cells population
por: Yu, Chang, et al.
Publicado: (2022)

Subcutaneous Inoculation of Echinococcus multilocularis Induces Delayed Regeneration after Partial Hepatectomy
por: Apaer, Shadike, et al.
Publicado: (2019)

Aldolase A Enhances Intrahepatic Cholangiocarcinoma Proliferation and Invasion through Promoting Glycolysis
por: Li, Xiang, et al.
Publicado: (2021)

C‐C motif chemokine ligand 5 confines liver regeneration by down‐regulating reparative macrophage‐derived hepatocyte growth factor in a forkhead box O 3a–dependent manner
por: Huang, Miao, et al.
Publicado: (2022)

Quantitative proteomics reveals Polygonum perfoliatum L. ameliorates hepatic steatosis by promoting PPARs/CPT1A/CPT2-mediated fatty acid β-oxidation
por: Liu, Guanjie, et al.
Publicado: (2023)

Partial hepatectomy induces delayed hepatocyte proliferation and normal liver regeneration in ovariectomized mice
por: Umeda, Makoto, et al.
Publicado: (2015)

Delayed Liver Regeneration after Partial Hepatectomy in Aged Nos2 Knockout Mice
por: Li, Deming, et al.
Publicado: (2017)

Aquaporin-9 facilitates liver regeneration following hepatectomy
por: Zhang, Bo, et al.
Publicado: (2022)

Ancient Herbal Formula Mahuang Lianqiao Chixiaodou Decoction Protects Acute and Acute-on-Chronic Liver Failure via Inhibiting von Willebrand Factor Signaling
por: Lin, Jiacheng, et al.
Publicado: (2022)

Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury
por: Li, Jichang, et al.
Publicado: (2020)

Impaired caudal fin‐fold regeneration in zebrafish deficient for the tumor suppressor Pten
por: Hale, Alexander James, et al.
Publicado: (2017)

Omega-3 fatty acid supplementation does not influence liver regeneration in rats after partial hepatectomy
por: Akbari, Mohammad, et al.
Publicado: (2018)

Biomechanics in liver regeneration after partial hepatectomy
por: Wu, Yi, et al.
Publicado: (2023)

GSK923295 as a potential antihepatocellular carcinoma agent causing delay on liver regeneration after partial hepatectomy
por: Tang, Jia-Cheng, et al.
Publicado: (2019)

Liver Regeneration after Partial Hepatectomy Is Not Impaired in Mice with Double Deficiency of Myd88 and IFNAR Genes
por: Vaquero, Javier, et al.
Publicado: (2011)

An Immunity-Related Gene Model Predicts Prognosis in Cholangiocarcinoma
por: Guo, Han, et al.
Publicado: (2022)

Silymarin Accelerates Liver Regeneration after Partial Hepatectomy
por: Wu, Jia-Ping, et al.
Publicado: (2015)

Liver Regeneration after Hepatectomy and Partial Liver Transplantation
por: Yagi, Shintaro, et al.
Publicado: (2020)

Functional assessment of liver regeneration after major hepatectomy
por: Rassam, Fadi, et al.
Publicado: (2022)

Atorvastatin provides a new lipidome improving early regeneration after partial hepatectomy in osteopontin deficient mice
por: Nuñez-Garcia, Maitane, et al.
Publicado: (2018)

The PTEN Conundrum: How to Target PTEN-Deficient Prostate Cancer
por: Turnham, Daniel J., et al.
Publicado: (2020)

DJ-1 promotes development of DEN-induced hepatocellular carcinoma and proliferation of liver cancer cells
por: Qiu, Bijun, et al.
Publicado: (2016)

PARK2 loss promotes cancer progression via redox-mediated inactivation of PTEN
por: Gupta, Amit, et al.
Publicado: (2017)

Potential Target miR-455 Delaying Arterial Stenosis Progression Through PTEN
por: Lin, Ruoran, et al.
Publicado: (2021)

PTEN inhibition and axon regeneration and neural repair
por: Ohtake, Yosuke, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_so4so8u76h2bposarmhu840vhb