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Combined PARP and Dual Topoisomerase Inhibition Potentiates Genome Instability and Cell Death in Ovarian Cancer

Although ovarian cancer is a rare disease, it constitutes the fifth leading cause of cancer death among women. It is of major importance to develop new therapeutic strategies to improve survival. Combining P8-D6, a novel dual topoisomerase inhibitor with exceptional anti-tumoral properties in ovaria...

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Detalles Bibliográficos
Autores principales:	Flörkemeier, Inken, Hillmann, Julia S., Weimer, Jörg P., Hildebrandt, Jonas, Hedemann, Nina, Rogmans, Christoph, Dempfle, Astrid, Arnold, Norbert, Clement, Bernd, Bauerschlag, Dirk O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505822/ https://www.ncbi.nlm.nih.gov/pubmed/36142413 http://dx.doi.org/10.3390/ijms231810503

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