Cargando…
A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex
The replication of human cytomegalovirus (HCMV) involves a process termed nuclear egress, which enables translocation of newly formed viral capsids from the nucleus into the cytoplasm. The HCMV core nuclear egress complex (core NEC), a heterodimer of viral proteins pUL50 and pUL53, is therefore cons...
Autores principales: | Alkhashrom, Sewar, Kicuntod, Jintawee, Stillger, Katharina, Lützenburg, Tamara, Anzenhofer, Christian, Neundorf, Ines, Marschall, Manfred, Eichler, Jutta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505826/ https://www.ncbi.nlm.nih.gov/pubmed/36145260 http://dx.doi.org/10.3390/ph15091040 |
Ejemplares similares
-
Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors
por: Alkhashrom, Sewar, et al.
Publicado: (2021) -
Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule
por: Kicuntod, Jintawee, et al.
Publicado: (2021) -
The Oligomeric Assemblies of Cytomegalovirus Core Nuclear Egress Proteins Are Associated with Host Kinases and Show Sensitivity to Antiviral Kinase Inhibitors
por: Kicuntod, Jintawee, et al.
Publicado: (2022) -
Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties
por: Marschall, Manfred, et al.
Publicado: (2020) -
The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity
por: Schweininger, Johannes, et al.
Publicado: (2022)