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Leucine Supplementation in Middle-Aged Male Mice Improved Aging-Induced Vascular Remodeling and Dysfunction via Activating the Sirt1-Foxo1 Axis

Vascular aging is associated with metabolic remodeling, and most studies focused on fatty acid and glucose metabolism. Based on our metabolomic data, leucine was significantly reduced in the aortas of aged mice. Whether leucine supplementation can reverse aging-induced vascular remodeling remains un...

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Detalles Bibliográficos
Autores principales:	Hao, Zhujing, Xu, Guiwen, Yuan, Mengyang, Tan, Ruopeng, Xia, Yunlong, Liu, Yang, Yin, Xiaomeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505861/ https://www.ncbi.nlm.nih.gov/pubmed/36145233 http://dx.doi.org/10.3390/nu14183856

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