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Systematic Evaluation of Voriconazole Pharmacokinetic Models without Pharmacogenetic Information for Bayesian Forecasting in Critically Ill Patients
Voriconazole (VRC) is used as first line antifungal agent against invasive aspergillosis. Model-based approaches might optimize VRC therapy. This study aimed to investigate the predictive performance of pharmacokinetic models of VRC without pharmacogenetic information for their suitability for model...
Autores principales: | Kallee, Simon, Scharf, Christina, Schatz, Lea Marie, Paal, Michael, Vogeser, Michael, Irlbeck, Michael, Zander, Johannes, Zoller, Michael, Liebchen, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505877/ https://www.ncbi.nlm.nih.gov/pubmed/36145667 http://dx.doi.org/10.3390/pharmaceutics14091920 |
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