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The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases

Background: The purpose of this study was to compare COVID-19 patients’ vessel caliber with that of normal lungs and lungs affected by other inflammatory and thromboembolic processes. Methods: between March and April 2020, 42 patients affected by COVID-19 pneumonia (COV-P) underwent CT scans of the...

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Autores principales: Ambrosetti, Maria-Chiara, Battocchio, Giulia, Montemezzi, Stefania, Cattazzo, Filippo, Bejko, Tissjana, Tacconelli, Evelina, Minuz, Pietro, Crisafulli, Ernesto, Fava, Cristiano, Mansueto, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505964/
https://www.ncbi.nlm.nih.gov/pubmed/36143250
http://dx.doi.org/10.3390/jpm12091465
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author Ambrosetti, Maria-Chiara
Battocchio, Giulia
Montemezzi, Stefania
Cattazzo, Filippo
Bejko, Tissjana
Tacconelli, Evelina
Minuz, Pietro
Crisafulli, Ernesto
Fava, Cristiano
Mansueto, Giancarlo
author_facet Ambrosetti, Maria-Chiara
Battocchio, Giulia
Montemezzi, Stefania
Cattazzo, Filippo
Bejko, Tissjana
Tacconelli, Evelina
Minuz, Pietro
Crisafulli, Ernesto
Fava, Cristiano
Mansueto, Giancarlo
author_sort Ambrosetti, Maria-Chiara
collection PubMed
description Background: The purpose of this study was to compare COVID-19 patients’ vessel caliber with that of normal lungs and lungs affected by other inflammatory and thromboembolic processes. Methods: between March and April 2020, 42 patients affected by COVID-19 pneumonia (COV-P) underwent CT scans of the lungs at Verona University Hospital for clinical indications. The lung images of four different groups of patients were compared (normal lung (NL), distal thromboembolism (DTE), and bacterial and fungal pneumonia (Bact-P, Fung-P)) by a radiologist with four years of experience. Results: The COV-P patients’ segmental and subsegmental vessels, evaluated as the ratio with the corresponding bronchial branch (V/B ratio), were larger, with respect to the NL the DTE groups, in the apparently healthy parenchyma, a result confirmed in the zones of opacification with respect to the Bact-P and Fung-P groups. Conclusions: This was the first study to show, by comparative analysis, that COVID-19 patients’ segmental and subsegmental vessel calibers are significantly enlarged. This is a distinctive feature of COVID-19 pneumonia, suggesting its distinct pathophysiology as compared to other inflammatory and thromboembolic diseases and alerting radiologists to consider it when evaluating the CT scans of suspected patients.
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spelling pubmed-95059642022-09-24 The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases Ambrosetti, Maria-Chiara Battocchio, Giulia Montemezzi, Stefania Cattazzo, Filippo Bejko, Tissjana Tacconelli, Evelina Minuz, Pietro Crisafulli, Ernesto Fava, Cristiano Mansueto, Giancarlo J Pers Med Article Background: The purpose of this study was to compare COVID-19 patients’ vessel caliber with that of normal lungs and lungs affected by other inflammatory and thromboembolic processes. Methods: between March and April 2020, 42 patients affected by COVID-19 pneumonia (COV-P) underwent CT scans of the lungs at Verona University Hospital for clinical indications. The lung images of four different groups of patients were compared (normal lung (NL), distal thromboembolism (DTE), and bacterial and fungal pneumonia (Bact-P, Fung-P)) by a radiologist with four years of experience. Results: The COV-P patients’ segmental and subsegmental vessels, evaluated as the ratio with the corresponding bronchial branch (V/B ratio), were larger, with respect to the NL the DTE groups, in the apparently healthy parenchyma, a result confirmed in the zones of opacification with respect to the Bact-P and Fung-P groups. Conclusions: This was the first study to show, by comparative analysis, that COVID-19 patients’ segmental and subsegmental vessel calibers are significantly enlarged. This is a distinctive feature of COVID-19 pneumonia, suggesting its distinct pathophysiology as compared to other inflammatory and thromboembolic diseases and alerting radiologists to consider it when evaluating the CT scans of suspected patients. MDPI 2022-09-07 /pmc/articles/PMC9505964/ /pubmed/36143250 http://dx.doi.org/10.3390/jpm12091465 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ambrosetti, Maria-Chiara
Battocchio, Giulia
Montemezzi, Stefania
Cattazzo, Filippo
Bejko, Tissjana
Tacconelli, Evelina
Minuz, Pietro
Crisafulli, Ernesto
Fava, Cristiano
Mansueto, Giancarlo
The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases
title The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases
title_full The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases
title_fullStr The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases
title_full_unstemmed The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases
title_short The Caliber of Segmental and Subsegmental Vessels in COVID-19 Pneumonia Is Enlarged: A Distinctive Feature in Comparison with Other Forms of Inflammatory and Thromboembolic Diseases
title_sort caliber of segmental and subsegmental vessels in covid-19 pneumonia is enlarged: a distinctive feature in comparison with other forms of inflammatory and thromboembolic diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505964/
https://www.ncbi.nlm.nih.gov/pubmed/36143250
http://dx.doi.org/10.3390/jpm12091465
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