The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition

It has been proposed that ATR kinase senses the completion of DNA replication to initiate the S/G2 transition. In contrast to this model, we show here that the TRESLIN-MTBP complex prevents a premature entry into G2 from early S-phase independently of ATR/CHK1 kinases. TRESLIN-MTBP acts transiently...

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Detalles Bibliográficos
Autores principales: Zonderland, Gijs, Vanzo, Riccardo, Amitash, Sampath, Martín-Doncel, Elena, Coscia, Fabian, Mund, Andreas, Lerdrup, Mads, Benada, Jan, Boos, Dominik, Toledo, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506001/
https://www.ncbi.nlm.nih.gov/pubmed/36049481
http://dx.doi.org/10.1016/j.molcel.2022.08.006

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