A Novel C-Type Lectin Receptor-Targeted α-Synuclein-Based Parkinson Vaccine Induces Potent Immune Responses and Therapeutic Efficacy in Mice

The progressive accumulation of misfolded α-synuclein (α-syn) in the brain is widely considered to be causal for the debilitating clinical manifestations of synucleinopathies including, most notably, Parkinson’s disease (PD). Immunotherapies, both active and passive, against α-syn have been develope...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidhuber, Sabine, Scheiblhofer, Sandra, Weiss, Richard, Cserepes, Mihály, Tóvári, József, Gadermaier, Gabriele, Bezard, Erwan, De Giorgi, Francesca, Ichas, Francois, Strunk, Dirk, Mandler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506002/
https://www.ncbi.nlm.nih.gov/pubmed/36146508
http://dx.doi.org/10.3390/vaccines10091432

Ejemplares similares

Ejemplares similares