Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting Haloperidol Exposure in Healthy and Disease Populations

The physiologically based pharmacokinetic (PBPK) approach can be used to develop mathematical models for predicting the absorption, distribution, metabolism, and elimination (ADME) of administered drugs in virtual human populations. Haloperidol is a typical antipsychotic drug with a narrow therapeut...

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Detalles Bibliográficos
Autores principales: Alasmari, Mohammed S., Alasmari, Fawaz, Alasmari, Abdullah F., Alshamsan, Aws, Alsanea, Sary, Rasool, Muhammad F., Alqahtani, Faleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506126/
https://www.ncbi.nlm.nih.gov/pubmed/36145543
http://dx.doi.org/10.3390/pharmaceutics14091795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506126/
https://www.ncbi.nlm.nih.gov/pubmed/36145543
http://dx.doi.org/10.3390/pharmaceutics14091795

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