Enhanced Immunogenicity of an Influenza Ectodomain Matrix-2 Protein Virus-like Particle (M2e VLP) Using Polymeric Microparticles for Vaccine Delivery

In this study, we demonstrate how encapsulating a conserved influenza ectodomain matrix-2 protein virus-like particle (M2e5x VLP) into a pre-crosslinked bovine serum albumin (BSA) polymeric matrix enhances in vitro antigen immunogenicity and in vivo efficacy. The spray-dried M2e5x VLP-loaded BSA mic...

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Detalles Bibliográficos
Autores principales: Gomes, Keegan Braz, Menon, Ipshita, Bagwe, Priyal, Bajaj, Lotika, Kang, Sang-Moo, D’Souza, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506217/
https://www.ncbi.nlm.nih.gov/pubmed/36146733
http://dx.doi.org/10.3390/v14091920

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