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Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice

Background: Chronic inflammation is an important driver in the progression of non-alcoholic steatohepatitis (NASH) and atherosclerosis. The complement system, one of the first lines of defense in innate immunity, has been implicated in both diseases. However, the potential therapeutic value of compl...

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Detalles Bibliográficos
Autores principales:	Seidel, Florine, Kleemann, Robert, van Duyvenvoorde, Wim, van Trigt, Nikki, Keijzer, Nanda, van der Kooij, Sandra, van Kooten, Cees, Verschuren, Lars, Menke, Aswin, Kiliaan, Amanda J., Winter, Johnathan, Hughes, Timothy R., Morgan, B. Paul, Baas, Frank, Fluiter, Kees, Morrison, Martine C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506266/ https://www.ncbi.nlm.nih.gov/pubmed/36142647 http://dx.doi.org/10.3390/ijms231810736

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