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Biological Evaluation of 3-Azaspiro[Bicyclo[3.1.0]Hexane-2,5′-Pyrimidines] as Potential Antitumor Agents

A series of heterocyclic compounds containing spirofused barbiturate and 3-azabicyclo[3.1.0]hexane frameworks have been studied as potential antitumor agents. Antiproliferative activity of products was screened in human erythroleukemia (K562), T lymphocyte (Jurkat), and cervical carcinoma (HeLa) as...

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Detalles Bibliográficos
Autores principales: Shmakov, Stanislav V., Latypova, Diana K., Shmakova, Tatiana V., Rubinshtein, Artem A., Chukin, Mark V., Zhuravskii, Sergei G., Knyazev, Nickolay A., Stepakov, Alexander V., Galagudza, Michael M., Boitsov, Vitali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506420/
https://www.ncbi.nlm.nih.gov/pubmed/36142688
http://dx.doi.org/10.3390/ijms231810759