Cargando…
The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021
COVID-19 causes thromboembolic complications that affect the patient’s prognosis. COVID-19 vaccines significantly improve the prognosis for the course of the infection. The aim of this study was to evaluate the impacts of patient characteristics, including COVID-19 vaccinations, on perioperative mor...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506468/ https://www.ncbi.nlm.nih.gov/pubmed/36143039 http://dx.doi.org/10.3390/jcm11185394 |
_version_ | 1784796730369245184 |
---|---|
author | Kaziród-Wolski, Karol Zając, Patrycja Zabojszcz, Michał Kołodziej, Agnieszka Sielski, Janusz Siudak, Zbigniew |
author_facet | Kaziród-Wolski, Karol Zając, Patrycja Zabojszcz, Michał Kołodziej, Agnieszka Sielski, Janusz Siudak, Zbigniew |
author_sort | Kaziród-Wolski, Karol |
collection | PubMed |
description | COVID-19 causes thromboembolic complications that affect the patient’s prognosis. COVID-19 vaccines significantly improve the prognosis for the course of the infection. The aim of this study was to evaluate the impacts of patient characteristics, including COVID-19 vaccinations, on perioperative mortality in acute coronary syndrome in Poland during the pandemic. We analyzed the data of 243,515 patients from the National Registry of Invasive Cardiology Procedures (Ogólnopolski Rejestr Procedur Kardiologii Inwazyjnej [ORPKI]). In this group, 7407 patients (21.74%) had COVID-19. The statistical analysis was based on a neural network that was verified by the random forest method. In 2020, the most significant impact on prognosis came from a diagnosis of unstable angina, a short period (<2 h) from pain occurrence to first medical contact, and a history of stroke. In 2021, the most significant factors were pre-hospital cardiac arrest, female sex, and a short period (<2 h) from first medical contact to coronary angiography. After adjusting for a six-week lag, a diagnosis of unstable angina and psoriasis were found to be relevant in the data from 2020, while in 2021, it was the time from the pain occurrence to the first medical contact (2–12 h) in non-ST segment elevation myocardial infarction and the time from first contact to balloon inflation (2–12 h) in ST-segment elevation myocardial infarction. The number of vaccinations was one of the least significant factors. COVID-19 vaccination does not directly affect perioperative prognosis in patients with acute coronary syndrome. |
format | Online Article Text |
id | pubmed-9506468 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95064682022-09-24 The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021 Kaziród-Wolski, Karol Zając, Patrycja Zabojszcz, Michał Kołodziej, Agnieszka Sielski, Janusz Siudak, Zbigniew J Clin Med Article COVID-19 causes thromboembolic complications that affect the patient’s prognosis. COVID-19 vaccines significantly improve the prognosis for the course of the infection. The aim of this study was to evaluate the impacts of patient characteristics, including COVID-19 vaccinations, on perioperative mortality in acute coronary syndrome in Poland during the pandemic. We analyzed the data of 243,515 patients from the National Registry of Invasive Cardiology Procedures (Ogólnopolski Rejestr Procedur Kardiologii Inwazyjnej [ORPKI]). In this group, 7407 patients (21.74%) had COVID-19. The statistical analysis was based on a neural network that was verified by the random forest method. In 2020, the most significant impact on prognosis came from a diagnosis of unstable angina, a short period (<2 h) from pain occurrence to first medical contact, and a history of stroke. In 2021, the most significant factors were pre-hospital cardiac arrest, female sex, and a short period (<2 h) from first medical contact to coronary angiography. After adjusting for a six-week lag, a diagnosis of unstable angina and psoriasis were found to be relevant in the data from 2020, while in 2021, it was the time from the pain occurrence to the first medical contact (2–12 h) in non-ST segment elevation myocardial infarction and the time from first contact to balloon inflation (2–12 h) in ST-segment elevation myocardial infarction. The number of vaccinations was one of the least significant factors. COVID-19 vaccination does not directly affect perioperative prognosis in patients with acute coronary syndrome. MDPI 2022-09-14 /pmc/articles/PMC9506468/ /pubmed/36143039 http://dx.doi.org/10.3390/jcm11185394 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kaziród-Wolski, Karol Zając, Patrycja Zabojszcz, Michał Kołodziej, Agnieszka Sielski, Janusz Siudak, Zbigniew The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021 |
title | The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021 |
title_full | The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021 |
title_fullStr | The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021 |
title_full_unstemmed | The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021 |
title_short | The Effect of COVID-19 on the Perioperative Course of Acute Coronary Syndrome in Poland: The Estimation of Perioperative Prognosis and Neural Network Analysis in 243,515 Cases from 2020 to 2021 |
title_sort | effect of covid-19 on the perioperative course of acute coronary syndrome in poland: the estimation of perioperative prognosis and neural network analysis in 243,515 cases from 2020 to 2021 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506468/ https://www.ncbi.nlm.nih.gov/pubmed/36143039 http://dx.doi.org/10.3390/jcm11185394 |
work_keys_str_mv | AT kazirodwolskikarol theeffectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT zajacpatrycja theeffectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT zabojszczmichał theeffectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT kołodziejagnieszka theeffectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT sielskijanusz theeffectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT siudakzbigniew theeffectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT kazirodwolskikarol effectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT zajacpatrycja effectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT zabojszczmichał effectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT kołodziejagnieszka effectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT sielskijanusz effectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 AT siudakzbigniew effectofcovid19ontheperioperativecourseofacutecoronarysyndromeinpolandtheestimationofperioperativeprognosisandneuralnetworkanalysisin243515casesfrom2020to2021 |