Cargando…

Influence of Genetic West African Ancestry on Metabolomics among Hypertensive Patients

Patients with higher genetic West African ancestry (GWAA) have hypertension (HTN) that is more difficult to treat and have higher rates of cardiovascular diseases (CVD) and differential responses to antihypertensive drugs than those with lower GWAA. The mechanisms underlying these disparities are po...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mehanna, Mai, McDonough, Caitrin W., Smith, Steven M., Gong, Yan, Gums, John G., Chapman, Arlene B., Johnson, Julie A., Cooper-DeHoff, Rhonda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506508/ https://www.ncbi.nlm.nih.gov/pubmed/36144188 http://dx.doi.org/10.3390/metabo12090783

Ejemplares similares

Metabolomics Signature of Plasma Renin Activity and Linkage with Blood Pressure Response to Beta Blockers and Thiazide Diuretics in Hypertensive European American Patients
por: Mehanna, Mai, et al.
Publicado: (2021)

Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response
por: Singh, Sonal, et al.
Publicado: (2019)

2246: Characterization of resistant hypertension in a statewide electronic health record-based database (OneFlorida)
por: McDonough, Caitrin W., et al.
Publicado: (2018)

Pairwise comparison of hydrochlorothiazide and chlorthalidone responses among hypertensive patients
por: Chekka, Lakshmi Manasa S., et al.
Publicado: (2022)

Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta‐Blockers in European Americans
por: Singh, Sonal, et al.
Publicado: (2019)

Large‐Scale Gene‐Centric Analysis Identifies Polymorphisms for Resistant Hypertension
por: Fontana, Vanessa, et al.
Publicado: (2014)

Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β‐Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil‐SR Trandolapril Study) Trials
por: Magvanjav, Oyunbileg, et al.
Publicado: (2017)

Optimizing Antihypertensive Medication Classification in Electronic Health Record-Based Data: Classification System Development and Methodological Comparison
por: McDonough, Caitrin W, et al.
Publicado: (2020)

Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients
por: Singh, Sonal, et al.
Publicado: (2018)

Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics
por: Sá, Ana Caroline C., et al.
Publicado: (2017)

Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies
por: Sá, Ana Caroline C., et al.
Publicado: (2018)

Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers
por: Cunningham, Patrick N., et al.
Publicado: (2019)

Lack of association of the HMGA1 IVS5-13insC variant with type 2 diabetes in an ethnically diverse hypertensive case control cohort
por: Karnes, Jason H, et al.
Publicado: (2013)

Melatonin Pathway and Atenolol‐Related Glucose Dysregulation: Is There a Correlation?
por: Chang, SW, et al.
Publicado: (2016)

Hypertension in Florida: Data From the OneFlorida Clinical Data Research Network
por: Smith, Steven M., et al.
Publicado: (2018)

Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study
por: Armstrong, Nicole D., et al.
Publicado: (2022)

Atenolol Induced HDL-C Change in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study
por: McDonough, Caitrin W., et al.
Publicado: (2013)

Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response
por: Turner, Stephen T, et al.
Publicado: (2012)

Impact of CYP2D6 polymorphisms on clinical efficacy & tolerability of metoprolol tartrate
por: Hamadeh, Issam S., et al.
Publicado: (2014)

Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics
por: Shahin, Mohamed H., et al.
Publicado: (2017)

Genome‐Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β‐Blockers
por: Shahin, Mohamed H., et al.
Publicado: (2018)

Genome-Wide Association Study Identifies Pharmacogenomic Loci Linked with Specific Antihypertensive Drug Treatment and New-Onset Diabetes
por: Chang, Shin-Wen, et al.
Publicado: (2016)

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans
por: Del-Aguila, J L, et al.
Publicado: (2014)

Optimizing Precision of Hypertension Care to Maximize Blood Pressure Control: A Pilot Study Utilizing a Smartphone App to Incorporate Plasma Renin Activity Testing
por: Mehanna, Mai, et al.
Publicado: (2020)

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs
por: Hiltunen, Timo P., et al.
Publicado: (2015)

Use of Electronic Health Records to Characterize Patients with Uncontrolled Hypertension in Two Large Health System Networks
por: Lu, Yuan, et al.
Publicado: (2023)

Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)
por: Singh, Sonal, et al.
Publicado: (2019)

In Reply: Probability of Reduced Follow-up Health Care Visits for Controlled Hypertensive Patients
por: Chamberlain, Alanna M., et al.
Publicado: (2023)

Association of Chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression
por: Duarte, Julio D., et al.
Publicado: (2012)

Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide
por: Duarte, Julio D, et al.
Publicado: (2012)

Simple Integer Risk Score to Determine Prognosis of Patients With Hypertension and Chronic Stable Coronary Artery Disease
por: Bavry, Anthony A., et al.
Publicado: (2013)

Medication Adherence—Still the Holy Grail
por: Cooper‐DeHoff, Rhonda M., et al.
Publicado: (2023)

Inference of Ancestries and Heterozygosity Proportion and Genotype Imputation in West African Cattle Populations
por: Gebrehiwot, Netsanet Z., et al.
Publicado: (2021)

Serum Metabolomic and Lipoprotein Profiling of Pancreatic Ductal Adenocarcinoma Patients of African Ancestry
por: Elebo, Nnenna, et al.
Publicado: (2021)

A Novel Simple Method for Determining CYP2D6 Gene Copy Number and Identifying Allele(s) with Duplication/Multiplication
por: Langaee, Taimour, et al.
Publicado: (2015)

Implications of Polymorphisms in the BCKDK and GATA‐4 Gene Regions on Stable Warfarin Dose in African Americans
por: Bargal, Salma A., et al.
Publicado: (2020)

Impact of Genetic Polymorphisms of SLC2A2, SLC2A5, and KHK on Metabolic Phenotypes in Hypertensive Individuals
por: Le, MyPhuong T., et al.
Publicado: (2013)

Characterizing the admixed African ancestry of African Americans
por: Zakharia, Fouad, et al.
Publicado: (2009)

Systematic Review of Genomic Associations with Blood Pressure and Hypertension in Populations with African-Ancestry
por: Singh, S., et al.
Publicado: (2021)

Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestry
por: Roelands, Jessica, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mdt9b0i1t3lvd9d96sll3bp7ha